The most likely side effects of Prednisone are a dry skin and nasal problems. Dry skin may occur when the form of prednisone (http://seoulfine.com) that is taken orally is converted into prednisolone, which can be absorbed into the body. According to some studies, Prednisone causes two times as many side effects as methotrexate. In addition, it also has a negative effect on cholesterol levels in the blood and decreases the ability of white blood cells to fight off infections